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Journal of Cardiovascular Pharmacology and Therapeutics

Journal of Cardiovascular Pharmacology and Therapeutics

eISSN: 19404034 | ISSN: 10742484 | Current volume: 27 | Current issue: 1 Frequency: Yearly


Journal of Cardiovascular Pharmacology and Therapeutics (JCPT) provides clinical and basic/translational investigators with novel insights into state-of-the-art therapeutic approaches for cardiovascular diseases. Topics of interest include:

    • Agents that Reduce Myocardial Infarct Size
    • Agents that Reduce Myocardial Remodeling
    • Angiotensin Converting Enzyme Inhibitors
    • Anticoagulants
    • Antihypertensive Therapy
    • Antiplatelet Agents
    • Arrhythmias
    • Atrial Fibrillation
    • Beta-Blocker Therapies
    • Cardiac Regeneration and Stem Cell Therapies
    • Cardioembolic Stroke
    • Cardiomyopathy
    • Cardioprotective Therapies
    • Cardiopulmonary Resuscitation
    • Cardiovascular Combination Therapies
    • Chronic Angina
    • Chronic Cardiac Ischemia
    • Congestive Heart Failure
    • Coronary Artery Disease
    • Coronary Revascularization
    • Heparin Therapies
    • Hypertension
    • Hypotension
    • Implantable Devices
    • Ischemic Conditioning: Pre-, Post- and Remote Conditioning
    • Ischemic Heart Disease
    • Myocardial Infarction
    • Percutaneous Coronary Interventions
    • Peripheral Arterial Disease
    • Preventive Cardiology
    • Risk Factor Management
    • NEW ****Anthacycline-Induced Cardiotoxicity****
    • NEW ****Muscular Dystrophy****
    • NEW ****Cardiovascular Epidemiology****
    • NEW ****Cost-Effectiveness Studies****
    • NEW ****Systematic Reviews and Meta-Analyses****

JCPT is a peer-reviewed, open access journal which features original clinical and basic/translational reports, cutting-edge review articles, and commentaries written by respected investigators in the field, as well as selected journal supplements focused on highly topical themes.

This journal flipped to open access in 2022. All material published between 1999 and 2021 is free access. Please see this page for information on reuse rights of archival material.

This journal is a member of the Committee on Publication Ethics (COPE).

Open access article processing charge (APC) information

Publication in the journal is subject to payment of an article processing charge (APC). The APC serves to support the journal and ensures that articles are freely accessible online in perpetuity under a Creative Commons licences.

The APC for this journal is currently an introductory rate of $1,000, discounted from the full rate of $2,000. The introductory rate is available for a limited time.

The APC is payable when a manuscript is accepted after peer review, before it is published. The APC is subject to taxes where applicable. Please see further details here.

Journal of Cardiovascular Pharmacology and Therapeutics is a peer-reviewed, open accessjournal that publishes original clinical research focused on new and emerging therapies for cardiovascular diseases, and original preclinical research with clear translational relevance. The journal also publishes state-of-the-art review articles, commentaries and editorials, as well as selected supplements and focused issues.

Karin Przyklenk, PhD Children's Hospital of Michigan; Central Michigan University, Detroit, MI, USA
Associate Editors
Bruno K. Podesser, MD Professor for Animal Research and Cardiac Surgery, Head Center for Biomedical Research, Medical University of Vienna, Austria
Richard S. Vander Heide, MD, PhD Service Line Medical Director, Pathology and Laboratory Service, Marshfield Clinic, Marshfield, WI, USA
Peter Whittaker, PhD Professor, Department of Emergency Medicine, Wayne State University School of Medicine, Detroit, MI, USA
Founding Editor
Bramah N. Singh, MD, DPhil, FRCP UCLA School of Medicine, Los Angeles, CA, USA
Editorial Board
Masanori Aikawa, PD, PhD Harvard Medical School, Boston, MA, USA
Amod Amritphale, MD University of South Alabama, Mobile, AL, USA
Inder Anand, MD University of Minnesota Medical School, Minneapolis, MN, USA
Jeffrey L. Anderson, MD, PhD University of Utah School of Medicine, Salt Lake City, UT, USA
Ioanna Andreadou, PhD National and Kapodistrian University of Athens, Athens, Greece
Ademuyiwa S Aromolaran, PhD Masonic Medical Research Institute, Utica, NY, USA
István Baczkó MD, PhD University of Szeged, Szeged, Hungary
John E. Baker, PhD Medical College of Wisconsin, Milwaukee, WI, USA
George Bakris, MD The University of Chicago Medicine, Chicago, IL, USA
Gary Baxter, PhD Cardiff University, Cardiff, Wales, UK
Theodore Berei, PharmD University of Wisconsin Hospitals and Clinics, Madison, WI, USA
Anil Bhandari, MD Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Deepak Bhatt, MD, MPH Brigham and Women's Hospital, Boston, MA, USA
Yochai Birnbaum, MD Baylor College of Medicine, Houston, TX, USA
William Boden, MD Boston University School of Medicine, Harvard Medical School and VA New England Healthcare System, Boston, MA, USA
Hans Erik Botker, MD, PhD University of Aarhus, Aarhus, Denmark
John Camm, MD, FRCP St. George’s Hospital Medical School, London, UK
David Cannom, MD Los Angeles Cardiology Associates, Los Angeles, CA, USA
Christopher Cannon, MD Brigham and Women’s Hospital, Boston, MA, USA
Alassandro Capucci, MD Università Politecnica delle Marche, Ancona, Italy
Bernard Chaitman, MD St. Louis University, St. Louis, MO, USA
Harry J.G.M. Crijns, MD, PhD Maastricht University Medical Center and CARIM, Maastricht, The Netherlands
Elyes Dahmane, PhD University of Maryland School of Pharmacy, Baltimore, MD, USA
Wangde Dai, MD Huntington Medical Research Institutes, Pasadena, CA, USA
Geoffrey De Couto, PhD Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, USA
Marcelo DiCarli, MD Brigham and Women’s Hospital, Boston, MA, USA
Yi Dong, MD, PhD Indiana University School of Medicine, Indianapolis, IN, USA
James Downey, PhD University of South Alabama, Mobile, AL, USA
Samuel Dudley, MD, PhD University of Minnesota, Minneapolis, MN, USA
Dirk Duncker, MD, PhD Erasmus University Medical Center Rotterdam, The Netherlands
Moses Elisaf, MD University of Ioannina Medical School, Ioannina, Greece
Uri Elkayam, MD Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Kathleen A. Fairman, MA, PhD Midwestern University, Glendale, AZ, USA
Loren Field, PhD Indiana University, Indianapolis, IN, USA
Stefan Frantz, MD, PhD Medical Hospital I, University Hospital, Würzburg, Germany
Habib Gamra, MD Fattouma Bourguiba University Hospital, Monastir, Tunisia
Candice Garwood, PharmD Wayne State University, Detroit, MI, USA
Zoltan Giricz Semmelweis University, Budapest, Hungary
Samuel Z. Goldhaber, MD Brigham and Women’s Hospital, Boston, MA, USA
Thomas Gremmel, MD Medical University of Vienna, Vienna, Austria
Gabriel B. Habib, MD Baylor College of Medicine, Houston, TX, USA
Sharon Hale, BS Huntington Medical Research Institutes, Pasadena, CA, USA
Gareth Hopkin, PhD Institute of Health Economics & University of Alberta, Edmonton, AB, Canada
Daniel A. Jones, MD, PhD Barts Heart Centre & Queen Mary University, London, UK
Attila Kiss, PhD Medical University of Vienna, Vienna, Austria
Petra Kleinbongard, PhD University of Essen Medical School, Germany
Robert A. Kloner, MD, PhD Huntington Medical Research Institutes, Pasadena, CA, USA
John Kostis, MD Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Cyrus R. Kumana, MBBS University of Hong Kong, Hong Kong, China
Michael Laflamme, MD, PhD University of Toronto, Toronto, ON, Canada
Richard A. Lange, MD Texas Tech University Health Sciences Center, El Paso, TX, USA
Sandrine Lecour, PhD University of Cape Town, Cape Town, South Africa
Jonathan Leor, MD School of Medicine, Tel-Aviv University, Sheba Medical Center, Tel Hashomer, Israel
Helmut Lieder, MD University of Duisburg Essen Institute of Pathophysiology, Essen, Germany
Matthew Linden, PhD University of Western Australia, Perth, Australia
Joseph Loscalzo, MD, PhD Brigham and Women’s Hospital, Boston, MA, USA
Douglas Losordo, MD Caladrius Biosciences, Rye Brook, NY, USA
Jawahar Mehta, MD, PhD University of Arkansas for Medical Sciences, Little Rock, AR, USA
Dimitri P. Mikhailidis, MD Royal Free and University College Medical School, London, UK
Michael Miller, MD University of Maryland, Baltimore, MD, USA
Tetsuji Miura, MD, PhD Sapporo Medical University School of Medicine, Sapporo, Japan
Emir Muzurovic, MD University of Montenegro Faculty of Medicine, Montenegro
Gerald Naccarelli, MD Penn State College of Medicine, Hershey, PA, USA
Haruaki Nakaya, MD, PhD Chiba University, Chiba, Japan
Michel Ovize, MD, PhD Hospital Louis Pradel and Claude Bernard University, Lyon, France
Jason Peart, PhD Griffith University, Brisbane, Queensland, Australia
Adam Perricone, MD, PhD Emory University, Atlanta, GA, USA
J. Geoffrey Pickering, MD, PhD Western University, London, ON, Canada
Alberto Polimeni, MD, PhD Magna Graecia University of Catanzaro, Italy
Fabrice Prunier, MD University of Angers, Angers, France
Arshed A. Quyyumi, MD Emory University School of Medicine, Atlanta, GA, USA
Thorsten Reffelmann, MD Klinikum Mittelmosel, Zell an der Mosel, Germany
Shereif Rezkalla, MD Marshfield Clinic, Marshfield, WI, USA
Clive Rosendorff, MD, PhD Icahn School of Medicine at Mount Sinai, New York, James J. Peters VA Medical Center, Bronx, NY, USA
Fadi Salloum, PhD Virginia Commonwealth University Medical Center, Richmond, VA, USA
Francesco Santoro, MD, PhD University of Foggia, Foggia, Italy
Ernst R. Schwarz, MD, PhD Cedars-Sinai Medical Center, Los Angeles, CA, USA
Prediman K. Shah, MD Cedars-Sinai Medical Center, Los Angeles, CA, USA
David Shavelle, MD Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Timothy Simpson, MD, PharmD Oregon Health & Science University, Portland, OR, USA
Pawan K. Singal, PhD, DSc University of Manitoba, Manitoba, Canada
Craig Smith, MD University of Massachusetts Medical School, Worcester, MA, USA
James R. Sowers, MD University of Missouri-Columbia School of Medicine, Columbia, MO, USA
Gregg W. Stone, MD Columbia University Medical Center and New York Presbyterian Hospital, New York, NY, USA
Peter H. Stone, MD Brigham and Women’s Hospital, Boston, MA, USA
John R. Teerlink, MD University of California, San Francisco, CA, USA
Christopher Toombs, PhD Proniras Corporation, Seattle, WA, USA
Dimitrios Tsiantoulas, PhD Medical University of Vienna, Austria
Orly Vardeny, PharmD University of Minnesota Medical School, Minneapolis, MN, USA
Renu Virmani, MD CVPath Institute, Inc., Gaithersburg, MD, USA
Xianwei Wang, MD, PhD Xinxiang Medical University, Xinxiang, China
Michael A. Weber, MD State University of New York Downstate College of Medicine, Brooklyn, NY, USA
Samuel Wickline, MD University of South Florida, Tampa, FL, USA
Loren Wold, PhD Ohio State University, Columbus, OH, USA
Derek M. Yellon, DSc Hatter Cardiovascular Institute, University College London Hospital & Medical School, London, UK
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  • Please read the guidelines below then visit Journal of Cardiovascular Pharmacology and Therapeutics (JCPT)’s submission site at to upload your manuscript. Please note that manuscripts not conforming to these guidelines may be returned. Remember you can log in to the submission site at any time to check on the progress of your paper through the peer review process.

    From January 2022, JCPT will become a fully open access journal. To facilitate this transition, all articles first submitted on or after September 8, 2021 will be subject to an open access article processing charge (APC) and published with a Creative Commons license. Articles submitted after this date will be charged an introductory APC of $1000.

    The APC is payable when a manuscript is accepted after peer review, before it is published. The APC is subject to taxes where applicable. Please see further details here

    SAGE Publishing disseminates high-quality research and engaged scholarship globally, and we are committed to diversity and inclusion in publishing. We encourage submissions from a diverse range of authors from across all countries and backgrounds.

    Only manuscripts of sufficient quality that meet the aims and scope of JCPT will be reviewed. 

    As part of the submission process you will be required to warrant that you are submitting your original work, that you have the rights in the work, and that you have obtained and can supply all necessary permissions for the reproduction of any copyright works not owned by you, that you are submitting the work for first publication in the Journal and that it is not being considered for publication elsewhere and has not already been published elsewhere. Please see our guidelines on prior publication. Note that JCPT may accept submissions of papers that have been posted on pre-print servers; please state in the Submission Letter that the manuscript has been posted on a pre-print server, and include the DOI for the preprint in both the Submission Letter and in the designated field in the manuscript submission system. Authors are not permitted to post an updated version of their paper on the preprint server while it is being peer reviewed for possible publication in the journal. If the article is accepted for publication, the author may re-use their work according to the journal's author archiving policy. If your paper is accepted, you must include a link on your preprint to the final version of your paper.

    This Journal is a member of the Committee on Publication Ethics.

    This Journal recommends that authors follow the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals formulated by the International Committee of Medical Journal Editors (ICMJE).

    If you have any questions about publishing with SAGE, please visit the SAGE Journal Solutions Portal.

    1. Open Access
    2. Article Processing Charge (APC)
    3. What do we publish?
      3.1 Aims & Scope
      3.2 Article types
      3.3 Writing your paper
      3.3.1 Make your article discoverable
    4. Editorial policies
      4.1 Peer review policy
      4.2 Authorship
      4.3 Acknowledgements
      4.3.1 Third party submissions
      4.3.2 Writing assistance
      4.4 Funding
      4.5 Declaration of conflicting interests
      4.6 Research ethics and patient consent
      4.7 Clinical trials
      4.8 Reporting guidelines
      4.9 Research data
    5. Publishing policies
      5.1 Publication ethics
      5.1.1 Plagiarism
      5.1.2 Prior publication
      5.2 Contributor's publishing agreement
    6. Preparing your manuscript for submission
      6.1 Formatting
      6.2 Artwork, figures and other graphics
      6.3 Supplemental material
      6.4 Reference style
      6.5 English language editing services
    7. Submitting your manuscript
      7.1 ORCID
      7.2 Information required for completing your submission
      7.3 Permissions
    8. On acceptance and publication
      8.1 SAGE Production
      8.2 Online publication
      8.3 Promoting your article
    9. Further information
      9.1 Appealing the publication decision

    1. Open Access

    JCPT is an open access, peer-reviewed journal. Each article accepted by peer review is made freely available online immediately upon publication, is published under a Creative Commons license and will be hosted online in perpetuity. Publication costs of the journal are covered by the collection of article processing charges which are paid by the funder, institution or author of each manuscript upon acceptance. There is no charge for submitting a paper to the journal.

    For general information on open access at SAGE please visit the Open Access page or view our Open Access FAQs.

    2. Article Processing Charge (APC)

    If, after peer review, your manuscript is accepted for publication, a one-time article processing charge (APC) is payable. This APC covers the cost of publication and ensures that your article will be freely available online in perpetuity under a Creative Commons license.

    The APC for this journal is $1000.

    The APC for Letters to the Editor is waived.

    The article processing charge (APC) is payable when a manuscript is accepted after peer review, before it is published. The APC is subject to taxes where applicable. Please see further details here.

    Your article may be eligible for a full or partial waiver due to SAGE’s participation in initiatives aimed at increasing accessibility to publication from lower-income countries.  Check here for further information about discounts and to see whether you may be eligible.

    3. What do we publish?

    3.1 Aims & Scope

    Before submitting your manuscript to JCPT, please ensure you have read the Aims & Scope. 

    Journal of Cardiovascular Pharmacology and Therapeutics is a peer-reviewed journal that publishes original clinical research focused on new and emerging therapies for cardiovascular diseases, and original preclinical research with clear translational relevance. The journal also publishes state-of-the-art review articles, commentaries and editorials.

    3.2 Article types

    JCPT publishes both original clinical studies and original preclinical investigations with clear translational relevance.  Areas of interest include (but are not limited to) cardioprotective therapies, stem cell therapy, regenerative cardiology, therapies for preventive cardiology (risk factor management), as well as antiplatelet, anticoagulation and antiarrhythmic therapies.

    Meta-analyses, Systematic Reviews, Editorials, Commentaries and Letters to the Editor will be given low priority and will be considered for publication on a highly selective basis. Case reports will not be accepted.

    For preclinical investigation, priority will be given to in vivo studies that focus on pharmacologic therapy for disease models. In general isolated cell studies alone, without an in vivo component, will be given low priority. All research involving animals must adhere to the ARRIVE2 Guidelines: see Section 4.8. Failure to comply with these Guidelines will result in rejection of the manuscript.

    Isolated cell studies alone, without an in vivo component, will be given low priority. JCPT will not consider studies of herbal remedies: these contributions should be submitted to journals of alternative medicine.

    JCPT accepts the following article types:

    • Original Manuscripts
      • Manuscripts should be written clearly and concisely: maximum 6,000 words (including Abstract, Figure Legends and References)
      • 200-250 word structured abstract
      • 5-6 keywords
      • Maximum 50 references
    • Reviews
      • Reviews should be written clearly and concisely: maximum 7,500 words (including Abstract, Figure Legends and References)
      • 200-250 word structured abstract
      • 5-6 keywords
      • Maximum 100 references
    • Letters to the Editor
      • Letters are considered for publication on a highly selective basis, and must comment on a recent paper published in JCPT
      • Letters reporting original data will not be accepted
      • Maximum 1,000 words (including References)
      • No abstract
      • 3-4 keywords
      • Maximum 5 references

    3.3 Writing your paper

    The SAGE Author Gateway has some general advice and on how to get published, plus links to further resources.

    3.3.1 Make your article discoverable

    For information and guidance on how to make your article more discoverable, visit our Gateway page on How to Help Readers Find Your Article Online

    4 Editorial policies

    4.1 Peer review policy

    JCPT operates a conventional single-anonymize reviewing policy in which the reviewer’s name is always concealed from the submitting author.

    Decisions on manuscripts will be taken as rapidly as possible. In general, Editors will seek advice from two or more expert reviewers about the scientific content and presentation of submitted articles.

    SAGE does not permit the use of author-suggested (recommended) reviewers at any stage of the submission process, be that through the web-based submission system or other communication.

    The Editor or members of the Editorial Board may occasionally submit their own manuscripts for possible publication in the journal. In these cases, the peer review process will be managed by alternative members of the Board and the submitting Editor/Board member will have no involvement in the decision-making process.

    JCPT is committed to delivering high quality, fast peer-review for your paper, and as such has partnered with Publons. Publons is a third party service that seeks to track, verify and give credit for peer review. Reviewers for JCPT can opt in to Publons in order to claim their reviews or have them automatically verified and added to their reviewer profile. Reviewers claiming credit for their review will be associated with the relevant journal, but the article name, reviewer’s decision and the content of their review is not published on the site. For more information visit the Publons website.

    4.2 Authorship

    Papers should only be submitted for consideration once all contributing authors give consent. Those submitting papers should carefully check that all those whose work contributed to the paper are acknowledged as contributing authors.

    The list of authors should include all those who can legitimately claim authorship. This is all those who:

    1. Made a substantial contribution to the concept or design of the work; or acquisition, analysis or interpretation of data,
    2. Drafted the article or revised it critically for important intellectual content,
    3. Approved the version to be published, 
    4. Each author should have participated sufficiently in the work to take public responsibility for appropriate portions of the content.

    Authors should meet the conditions of all of the points above. When a large, multicenter group has conducted the work, the group should identify the individuals who accept direct responsibility for the manuscript. These individuals should fully meet the criteria for authorship. 

    Acquisition of funding, collection of data, or general supervision of the research group alone does not constitute authorship, although all contributors who do not meet the criteria for authorship should be listed in the Acknowledgments section. Please refer to the International Committee of Medical Journal Editors (ICMJE) authorship guidelines for more information on authorship.

    4.3 Acknowledgements

    All contributors who do not meet the criteria for authorship should be listed in an Acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, or a department chair who provided only general support. 

    Any acknowledgements should appear first at the end of your article prior to your Declaration of Conflicting Interests (if applicable), any notes and your References.

    4.3.1 Third party submissions

    Where an individual who is not listed as an author submits a manuscript on behalf of the author(s), a statement must be included in the Acknowledgements section of the manuscript and in the accompanying cover letter. The statements must:

    • Disclose this type of editorial assistance – including the individual’s name, company and level of input
    • Identify any entities that paid for this assistance
    • Confirm that the listed authors have authorized the submission of their manuscript via third party and approved any statements or declarations, e.g. conflicting interests, funding, etc.

    Where appropriate, SAGE reserves the right to deny consideration to manuscripts submitted by a third party rather than by the authors themselves

    4.3.2 Writing assistance

    Individuals who provided writing assistance, e.g. from a specialist communications company, do not qualify as authors and so should be included in the Acknowledgements section. Authors must disclose any writing assistance – including the individual’s name, company and level of input – and identify the entity that paid for this assistance. It is not necessary to disclose use of language polishing services.

    4.4 Funding

    JCPT requires all authors to acknowledge their funding in a consistent fashion under a separate heading.  Please visit the Funding Acknowledgements page on the SAGE Journal Author Gateway to confirm the format of the acknowledgment text in the event of funding, or state that: “This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.” 

    4.5 Declaration of conflicting interests

    It is the policy of JCPT to require a declaration of conflicting interests from all authors enabling a statement to be carried within the paginated pages of all published articles. 

    Please ensure that a ‘Declaration of Conflicting Interests’ statement is included at the end of your manuscript, after any acknowledgements and prior to the references. If no conflict exists, please state that: “The Author(s) declare(s) that there is no conflict of interest.” For guidance on conflict of interest statements, please see the ICMJE recommendations here.

    4.6 Research ethics and patient consent

    Medical research involving human subjects must be conducted according to the World Medical Association Declaration of Helsinki. A statement that the protocol and informed consent were reviewed and approved by an IRB (Institutional Review Board) should be included in the methods section.

    Submitted manuscripts should conform to the ICMJE Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals, and all papers reporting animal and/or human studies must state in the methods section that the relevant Ethics Committee or Institutional Review Board provided (or waived) approval. Please ensure that you have provided the full name and institution of the review committee, in addition to the approval number.

    For research articles, authors are also required to state in the methods section whether participants provided informed consent and whether the consent was written or verbal.

    Information on informed consent to report individual cases or case series should be included in the manuscript text. A statement is required regarding whether written informed consent for patient information and images to be published was provided by the patient(s) or a legally authorized representative. Please do not submit the patient’s actual written informed consent with your article, as this in itself breaches the patient’s confidentiality. The Journal requests that you confirm to us, in writing, that you have obtained written informed consent but the written consent itself should be held by the authors/investigators themselves, for example in a patient’s hospital record. The confirmatory letter may be uploaded with your submission as a separate file.

    Please also refer to the ICMJE Recommendations for the Protection of Research Participants.

    All research involving animals submitted for publication must be approved by an ethics committee with oversight of the facility in which the studies were conducted. The journal has adopted the Consensus Author Guidelines on Animal Ethics and Welfare for Veterinary Journals published by the International Association of Veterinary Editors. A statement to this effect needs to be described in the methods section. In addition a statement that the protocol was approved by an IACUC (Institutional Animal Care and Use Committee) is required. 

    4.7 Clinical trials

    JCPT conforms to the ICMJE requirement that clinical trials are registered in a WHO-approved public trials registry at or before the time of first patient enrollment as a condition of consideration for publication. The trial registry name and URL, and registration number must be included at the end of the abstract. The registration number and registry name for clinical trials should be provided in the methods section.

    4.8 Reporting guidelines

    The relevant EQUATOR Network reporting guidelines should be followed depending on the type of study. For example, all randomized controlled trials submitted for publication should include a completed CONSORT flow chart as a cited figure and the completed CONSORT checklist should be uploaded with your submission as a supplemental file. Systematic reviews and meta-analyses should include the completed PRISMA flow chart as a cited figure and the completed PRISMA checklist should be uploaded with your submission as a supplemental file. The EQUATOR wizard can help you identify the appropriate guideline. For all research involving animals, authors must include a sentence in the Methods section of the manuscript, affirming that all investigations adhere to the  ARRIVE2 Guidelines. Failure to comply with the ARRIVE Guidelines will result in rejection of the manuscript

    Other resources can be found at NLM’s Research Reporting Guidelines and Initiatives.

    4.9 Research data

    The journal is committed to facilitating openness, transparency and reproducibility of research, and has the following research data sharing policy. For more information, including FAQs please visit the SAGE Research Data policy pages.

    Subject to appropriate ethical and legal considerations, authors are encouraged to:

    • share your research data in a relevant public data repository
    • include a data availability statement linking to your data. If it is not possible to share your data, we encourage you to consider using the statement to explain why it cannot be shared.
    • cite this data in your research

    5. Publishing policies

    5.1 Publication ethics

    SAGE is committed to upholding the integrity of the academic record. We encourage authors to refer to the Committee on Publication Ethics’ International Standards for Authors and view the Publication Ethics page on the SAGE Author Gateway.

    5.1.1 Plagiarism

    JCPT and SAGE take issues of copyright infringement, plagiarism or other breaches of best practice in publication very seriously. We seek to protect the rights of our authors and we always investigate claims of plagiarism or misuse of published articles. Equally, we seek to protect the reputation of the journal against malpractice. Submitted articles may be checked with duplication-checking software. Where an article, for example, is found to have plagiarized other work or included third-party copyright material without permission or with insufficient acknowledgement, or where the authorship of the article is contested, we reserve the right to take action including, but not limited to: publishing an erratum or corrigendum (correction); retracting the article; taking up the matter with the head of department or dean of the author's institution and/or relevant academic bodies or societies; or taking appropriate legal action.

    In order to help assure that all manuscripts are original submitted papers are routinely screened using a computerize plagiarism tracking system known as iThenticate. This program identifies phrases, sentences, and paragraphs that have previously been published, including the authors' own work. The program generates a similarity index. If the similarity index is greater than ~33% after removal of the bibliography, the manuscript will be returned to the authors without a review.

    5.1.2 Prior publication

    If material has been previously published it is not generally acceptable for publication in a SAGE journal. However, there are certain circumstances where previously published material can be considered for publication. Please refer to the guidance on the SAGE Author Gateway or if in doubt, contact the Editor at the address given below.

    5.2 Contributors publishing agreement

    Before publication SAGE requires the author as the rights holder to sign a Journal Contributor’s Publishing Agreement.  JCPT publishes manuscripts under Creative Commons licenses. The standard license for the journal is Creative Commons by Attribution Non-Commercial (CC BY-NC), which allows others to re-use the work without permission as long as the work is properly referenced and the use is non-commercial. For more information, you are advised to visit SAGE's OA licenses page. Alternative license arrangements are available, for example, to meet particular funder mandates, made at the author’s request.

    6 Preparing your manuscript for submission

    6.1 Formatting

    The preferred format for your manuscript is Word.

    Manuscripts are accepted for consideration on the condition that they are contributed solely to JCPT. No substantial part of a paper may have been published elsewhere, including being published in another language besides English, except as a scientific abstract. All work must be original. Previously published long phrases, sentences, and paragraphs (including the author’s own work) must be properly cited in AMA format—anything else will be considered unacceptable. A direct quote of no more than 4 lines from textual material should be enclosed in double quotation marks; if longer than 4 lines it should be formatted as a block extract. Always verify the quote against the original source, and the citation should include the exact page number(s) of the source. Such directly quoted material should be used sparingly. The receipt of your manuscript by the Journal will be acknowledged and a decision regarding its status made as soon as possible. All manuscripts are subject to editorial review. Manuscripts must be written in acceptable English. Manuscripts submitted in poor English will be returned without review. Some manuscripts that are deemed inappropriate for the journal or very low priority by the editorial staff may be returned without review.

    Submission Letter

    The manuscript must be accompanied by a cover letter that states (1) all the authors have read and approved the final manuscript, (2) all authors have read and approve of the data being presented in the manuscript, and (3) the full name, address, e-mail address, phone, and fax number of the individual to whom correspondence concerning the manuscript is to be sent. The cover letter must also specifically state and verify that the paper being submitted has not been previously published in whole or in part in any form, including being published in another language besides English, is not under consideration for publication elsewhere, and is original. If the manuscript has been posted on a pre-print server, this must be acknowledged and the DOI for the preprint must be included in the cover letter. The cover letter should be addressed to

    Karin Przyklenk, PhD
    Journal of Cardiovascular Pharmacology and Therapeutics
    Children's Hospital of Michigan
    Central Michigan University
    Detroit, MI

    Title Page

    On the title page, please include all of the following information:

    1. The names, degrees, and professional affiliation (position, department, institution, place) of all authors.
    2. The name of the institution where the work reported was done.
    3. Acknowledgment of grant support when appropriate.
    4. Complete mailing address, telephone, and fax of corresponding author and e-mail addresses of all authors.

    The American Medical Association (AMA) Manual of Style, is the standard source of style. For more information on the AMA Manual of Style, please visit


    The abstract should be no longer than 250 words in length. The abstract should summarize the main points of the paper and be descriptive, narrative, and informative and should include only information that is in the article. Avoid abbreviations. At the bottom of the abstract, please also submit a maximum of 5 keywords for your article.

    Body of the Text

    For most original manuscripts, the subheadings Introduction, Methods and Materials, Results, Discussion, and Conclusion or Summary are suggested. The introduction should be no longer than 2-3 paragraphs and should provide background and rationale for the study and specifically state the purpose of the study. The methods section should describe what statistical tests were used. The text of the paper should be no longer than 15-20 double-spaced typed pages in most cases. All tables and figures should be referenced in the main text in the order in which they appear. The discussion should stress what is new in the paper and relate the author’s findings to the existing literature. The discussion should show how the findings add to the existing knowledge base of the subject under study.


    Please avoid excessive and unnecessary abbreviations. Keep them to a minimum. The first time an abbreviation is used it should be defined.


    All tables must be cited in text. Tables are to be numbered with Arabic numerals (Table 1, Table 2) in order of their text citation. Each table should be typed (double-spaced throughout) on a separate sheet of paper and should have a title. Use spaces, not vertical rules, to separate columns. Each table should have a legend in sufficient detail to allow understanding without reference to the text.

    6.2 Artwork, figures, other graphics

    For guidance on the preparation of illustrations, pictures and graphs in electronic format, please visit SAGE’s Manuscript Submission Guidelines.

    Figures supplied in color will appear in color online.

    Acceptable file formats include the following: TIFF, JPEG, and PDF. Microsoft application files are acceptable for vector art (line art).

    Scanned Images
    Line art (black and white) images should be scanned as a bitmap at 900ppi. Photos should be scanned as grayscale or CMYK at 300ppi.

    6.3 Supplemental material

    This journal is able to host additional materials online (e.g. datasets, podcasts, videos, images etc.) alongside the full-text of the article. For more information please refer to our guidelines on submitting supplemental files.

    6.4 Reference style

    JCPT adheres to the AMA Manual of Style. View the guide here to ensure your manuscript conforms to this style.

    In the text, please use a superscripted number that correlates with the reference at the end of the manuscript. When several references are cited simultaneously in the text, you can list the superscripted numbers together, for example, ‘‘Many researchers have debated this subject.1,2,5,9’’ Use ‘‘et al’’ for cites of 3 authors or more in text. However, in the references, list up to 6 authors. If there are more than 6 authors, list the first 3 authors and then ‘‘et al’’. Type references double-spaced at the end of the manuscript numbered in order of appearance in the manuscript. Unpublished data and personal communications should be given as references. Manuscripts in press may be referenced; however, manuscripts that have been submitted for publication but have not been accepted yet should not be referenced. Avoid quoting abstracts where possible.

    Michaud G, McGowan JL, van der Jagt R, et al. Are therapeutic decisions supported by evidence from health care research? Arch Intern Med. 1998;158:1665-1668.

    Book Chapters
    Cole BR. Cystinosis and cystinuria. In: Jacobson HR, Striker GE, Klahr S, eds. The Principles and Practice of Nephrology. Philadelphia, PA: BC Decker Inc; 1991:396-403.

    Sackett DL, Straus SE, Richardson WS, et al. Evidence-based Medicine: How to Practice and Teach EBM. 2nd ed. New York, NY: Churchill Livingstone; 2000.

    6.5 English language editing services

    Authors seeking assistance with English language editing, translation, or figure and manuscript formatting to fit the journal’s specifications should consider using SAGE Language Services. Visit SAGE Language Services on our Journal Author Gateway for further information. 

    7 Submitting your manuscript

    JCPT is hosted on SAGE Track, a web based online submission and peer review system powered by ScholarOne™ Manuscripts. Visit to login and submit your article online. 

    IMPORTANT: Please check whether you already have an account in the system before trying to create a new one. If you have reviewed or authored for the journal in the past year it is likely that you will have had an account created.  For further guidance on submitting your manuscript online please visit ScholarOne Online Help.

    7.1 ORCID

    As part of our commitment to ensuring an ethical, transparent and fair peer review process SAGE is a supporting member of ORCID, the Open Researcher and Contributor ID. ORCID provides a unique and persistent digital identifier that distinguishes researchers from every other researcher, even those who share the same name, and, through integration in key research workflows such as manuscript and grant submission, supports automated linkages between researchers and their professional activities, ensuring that their work is recognized.

    The collection of ORCID IDs from corresponding authors is now part of the submission process of this journal. If you already have an ORCID ID you will be asked to associate that to your submission during the online submission process. We also strongly encourage all co-authors to link their ORCID ID to their accounts in our online peer review platforms. It takes seconds to do: click the link when prompted, sign into your ORCID account and our systems are automatically updated. Your ORCID ID will become part of your accepted publication’s metadata, making your work attributable to you and only you. Your ORCID ID is published with your article so that fellow researchers reading your work can link to your ORCID profile and from there link to your other publications.

    If you do not already have an ORCID ID please follow this link to create one or visit our ORCID homepage to learn more.

    7.2 Information required for completing your submission

    You will be asked to provide contact details and academic affiliations for all co-authors via the submission system and identify who is to be the corresponding author. These details must match what appears on your manuscript. The affiliation listed in the manuscript should be the institution where the research was conducted. If an author has moved to a new institution since completing the research, the new affiliation can be included in a manuscript note at the end of the paper. At this stage please ensure you have included all the required statements and declarations and uploaded any additional supplemental files (including reporting guidelines where relevant).

    7.3 Permissions

    Please also ensure that you have obtained any necessary permission from copyright holders for reproducing any illustrations, tables, figures or lengthy quotations previously published elsewhere. For further information including guidance on fair dealing for criticism and review, please see the Copyright and Permissions page on the SAGE Author Gateway.

    8 On acceptance and publication

    If your paper is accepted for publication after peer review, you will first be asked to complete the contributor’s publishing agreement. Once your manuscript files have been checked for SAGE Production, the corresponding author will be asked to pay the article processing charge (APC) via a payment link. Once the APC has been processed, your article will be prepared for publication and can appear online within an average of 30 days. Please note that no production work will occur on your paper until the APC has been received.

    8.1 SAGE production

    Your SAGE Production Editor will keep you informed as to your article’s progress throughout the production process. Proofs will be made available to the corresponding author via our editing portal or by email, and corrections should be made directly or notified to us promptly. Authors are reminded to check their proofs carefully to confirm that all author information, including names, affiliations, sequence and contact details are correct, and that Funding and Conflict of Interest statements, if any, are accurate. 

    8.2 Online publication

    One of the many benefits of publishing your research in an open access journal is the speed to publication. With no page count constraints, your article will be published online in a fully citable form with a DOI number as soon as it has completed the production process. At this time it will be completely free to view and download for all.

    8.3 Promoting your article

    Publication is not the end of the process! You can help disseminate your paper and ensure it is as widely read and cited as possible. The SAGE Author Gateway has numerous resources to help you promote your work. Visit the Promote Your Article page on the Gateway for tips and advice.  

    9 Further information

    Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the JCPT editorial office as follows: 

    Supriya Bidola, Peer Review Associate

    9.1 Appealing the publication decision

    Editors have very broad discretion in determining whether an article is an appropriate fit for their journal. Many manuscripts are declined with a very general statement of the rejection decision. These decisions are not eligible for formal appeal unless the author believes the decision to reject the manuscript was based on an error in the review of the article, in which case the author may appeal the decision by providing the Editor with a detailed written description of the error they believe occurred.

    If an author believes the decision regarding their manuscript was affected by a publication ethics breach, the author may contact the publisher with a detailed written description of their concern, and information supporting the concern, at